The so-called “Johnson and Johnson” The effectiveness of the booster is questionable

9

According to a paper published Wednesday, for those who have been vaccinated with Johnson & Johnson at Covid-19, it may be best to take the Covid-19 vaccine instead of the Pfizer or Moderna vaccine. This so-called The results of a study on the effectiveness of boosters are based on a federal clinical trial of vaccines approved in the United States. The paper has not yet been reviewed by colleagues and, therefore, has not yet been published in a scientific journal.

Specialists from the US Food and Drug Administration (FDA), the chief regulator of the United States, will release a final report on the effectiveness and safety of the Johnson & Johnson vaccine booster on Friday. The panel consists not of federal staff but of independent experts. In the event of a positive decision, the matter will be referred to the US Centers for Disease Control and Prevention (CDC) for approval.

Shortly before, the Food and Drug Administration released the presentation presentation material for October 14-15. It also contains the results of a study by Johnson & Johnson himself on the use of his own vaccine booster dose.

Specialists think that there will be a heated debate on the differences between these two studies. At stake is the selection of an additional dose of vaccine for at least 15 million Americans who have been vaccinated with the Johnson & Johnson single-dose Covid-19 vaccine. However, it is not excluded that the so-called Boosters are still approved because the “Johnson & Johnson” vaccine is also less but still effective.

As for the federal study, 9 groups of 50-50 people were observed in it. Each received different combinations of 3 vaccines authorized in the United States. The booster dose in the three groups was made with the same vaccine. In the other six – another company’s booster.

In those who first got the Johnson & Johnson vaccine and then the Moderna booster, the number of antibodies increased 76-fold in the next 15 days; In case of “Pfizer” booster – 35 times; In the case of the “Johnson and Johnson” booster only 4 times.

The author of the federal study is the National Institutes of Health. A small number of participants are named among the research limits. In addition, immunity in the body was measured solely on the basis of antibody production. Scientists have not checked how well he trained the so-called. Booster cells in detecting infection and neutralizing it.

.