Researchers at Fiocruz analyzed 250 genetic codes for almost a year; P.1 mutation is considered by experts to be more transmissible
A study by researchers from the Oswaldo Cruz Foundation (Fiocruz) reveals that adults infected with the new coronavirus detected in the state of Amazon have a viral load ten times greater than adults infected by other versions of Covid-19. The greater amount of viruses in the body is not related to the severity of the patient’s health condition, but rather to the ease of transmissibility of the disease. The survey is available for consultation on social networks.
250 genetic codes were analyzed during an interval of almost a year, between the first peak of the disease, in April 2020, and the second, at the end of last year and the beginning of 2021. One of the researchers, Tiago Graf explains, in his profile on Twitter, that the variant, called P.1, generates a higher viral load among adults. “The comparison of the patients clearly shows that infection by P.1 generates a higher viral load in adults. In the elderly, the significance was small or none. Perhaps because our sample size was smaller in this group or because these individuals are equally vulnerable to all strains, ”says the publication.
In another tweet, Graf shows a graph in which it is possible to compare the viral load between patients with the P.1 variant and others with another version of the virus. In the image, the smaller the amount on the vertical axis (Ct), the greater the viral load. Despite appearing in Amazonas, at least 18 states have already verified the existence of patients infected with this variant, considered by specialists as more transmissible.
To better understand what led P.1 to this success in dissemination, we compared the amount of virus in samples from patients P.1 and not P.1. We did this by the Ct of the PCR test (the lower the Ct, the greater the viral load).
— Tiago Gräf (@GrafTiago)