The accumulation of the Corona virus, Covid-19, in the lungs appears to be the main cause of death in patients, as a new study has ended previous assumptions about the cause of death.
And the Spanish magazine “Sapir Vivier” published a report in which it spoke about the danger that the quantities of the virus, which are concentrated in the lungs, can cause. In addition, it is a pivotal factor in the deterioration of the health status of patients.
The study, according to the translation of the newspaper “Watan”, concluded that the accumulation of the coronavirus in the lungs is likely to be behind the severe death rates, which were recently seen in the world.
Serious complications in case of infection with the virus
It was said that the real cause of death from the Corona virus was not the disease itself, but the subsequent complications it causes, which are as follows:
- Overreaction of the immune system, the so-called cytokine storm.
- Bacterial pneumonia, which is caused by respiratory problems
A study led by New York University concluded that Prime Time Zone who died of coronavirus had, on average, 10 times as many viruses in the lower respiratory tract (trachea, bronchi, and lungs), compared to critically ill patients, yet they survived.
For the study authors, there is no clear evidence that complications from bacterial infection were the cause of death. In this context, Dr. Imran Suleiman, the author of the research, stressed that “the inability of the body to deal with such a large amount of viruses in the lungs is the main cause of death.”
Use of antivirals
The aim of the study was to determine how dangerous the deadly virus is by itself, and not as a cause of other serious problems, such as stroke or pneumonia.
For the study, researchers collected bacterial and fungal samples from the lungs of 589 men and women who were hospitalized at NYU Langone facilities in Manhattan and Long Island.
All patients underwent standard treatments and were placed on ventilators. These are patients admitted between March and June 2020.
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Despite previous concerns that the virus might prompt the immune system to attack the body’s lung tissue and lead to dangerous levels of inflammation, the investigators found no evidence that this was a major contributor to the deaths of those infected in the studied group, as the researchers noted that the strength of the immune response It seemed to be proportional to the amount of virus in the lungs.
According to the doctor, the way the immune system responds is proportional to the amount of virus that accumulates in the lungs. But he explained that “what should be done as a priority is treatment to reduce the viral load and stimulate the patient’s immune response.”
Experts attribute the high death rate seen in other viral epidemics, such as the Spanish flu in 1918 and swine flu in 2009, to a secondary bacterial infection.
These precedents may have influenced the justification of the possible causes of deaths, which occurred during the spread of this epidemic. That is why the researchers considered it necessary to carry out a comprehensive analysis, relying exclusively on the data, without assuming anything.
In contrast, the authors did not attempt to correct the reports, which were issued especially in the first wave, when the death rate was higher. So this study focused on patients who contracted COVID-19 in the first wave, who outlived or died in the first two weeks of hospitalization.
Moreover, a cytokine storm or infection may have a greater impact on the death of patients who have been in intensive care for a longer time.
Immune system failure
One of the findings of this research, which may be important, is that something goes wrong with the immune system.
The analysis found that patients who died did not have an adequate defensive response. This involves the production of certain proteins of the immune system, which are responsible for remembering invading microorganisms to warn other cells.
The study revealed that those who died had, on average, 50 percent less of a type of immune chemical targeting the Corona virus, compared to Covid-19 patients who survived the disease.
These custom proteins are part of the body’s adaptive immune system, a subset of cells and chemicals that “remember” newly encountered microbe invasion, making the body better prepared for future exposures.
These results indicate that a problem with the adaptive immune system prevents it from effectively fighting the Corona virus. The researchers say that if we can identify the source of this problem, we may be able to find an effective treatment that works by strengthening the body’s defenses.
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