Recent clinical research has found that Prime Time Zone with poor dental hygiene have a higher risk of developing Alzheimer’s disease.
and published a magazine “Medico PlusSpanish, a report in which she highlighted the human body, which consists of 80 members, each specialized in a very specific function.
But this does not mean that they are unrelated members. Therefore, we must understand that our body is a network of cohesive organs, which communicate with each other in some way, despite their different functions.
In its report, which was translated by “Watan” newspaper, the magazine indicated that the health of some members, and the extent of their safety, can be completely linked to the health of another member of the body, even if there is no direct affinity.
Can the mouth determine how healthy our brain is?
Dental hygiene habits can prevent the early onset of Alzheimer’s disease, a neurological disease that is the leading cause of dementia in the world.
In fact, this is the result of a study conducted by the University of Bergen in 2019, where researchers claim that Prime Time Zone with gingivitis have a higher risk of developing Alzheimer’s disease, compared to those with optimal oral hygiene.
Gingivitis and Alzheimer’s disease
A University of Bergen study found that there is a link between gingivitis and Alzheimer’s disease. But one may ask, how can oral infections increase the risk of suffering from such dreaded neurological diseases.
What is gingivitis?
Gingivitis is one of the most common oral infections. Gingivitis, sometimes called gum disease or periodontal disease, describes cases of bacterial accumulation in the oral cavity that, if not treated properly, can eventually lead to tooth loss, as a result of damage that affects the layer that encases the tooth.
Although it affects about 90 percent of the world’s population, this should not frighten us, because most Prime Time Zone have minor problems, and the problem is only if this infection develops, and we do not take the necessary health measures.
Furthermore, gingivitis is an early stage of gum disease, which manifests as inflammation of the gum line that, if left untreated, can progress to the point where the inflammation becomes harmful to the strength and health of the bone that surrounds and supports your teeth. Moreover, the direct cause of gingivitis is the plaque that accumulates on your teeth due to incorrect brushing after meals. It is worth noting that plaques are a thin, sticky, and colorless layer of bacteria that forms on the teeth and gums by mixing the remaining food particles with saliva.
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According to the University of Bergen study, there is a type of germ that directly causes Alzheimer’s disease, Porphyromonas gingivalis or Perforator gingivalis is a Gram-negative oral anaerobic bacteria that causes gingivitis, and it is a member of more than 500 bacterial species that live in the oral cavity. These anaerobic bacteria are a natural member of the oral microbiome, however they can become very destructive.
Accordingly, the number of these bacteria begins to grow in the gingival furrow, which is the area of contact between the gum and the tooth surface. The gingival foramen begins to form enzymatic compounds and feeds on the gums, causing them to lose their primary color (and become redder) and the teeth to begin to “loosen up”, slowly losing their point of support.
At the same time, secondary symptoms such as bad breath and sensitivity to cold foods and drinks appear, not to mention that with every brushing, the gums can bleed heavily.
But what is the relationship between gingivitis and the risk of Alzheimer’s disease?
What is Alzheimer’s disease?
Alzheimer’s disease is one of the most frightening diseases in the world because it makes you lose your memories and it is the leading cause of dementia in the world.
Alzheimer’s disease is a neurological disorder characterized by a gradual deterioration of brain cells. It is also a health condition, which sometimes leads to the loss of life. It is estimated that about 50 million Prime Time Zone around the world suffer from dementia, and that up to 70 percent of them, have reached this stage due to Alzheimer’s disease.
Cases often appear after 65 years of age, and the disease causes a slow but somewhat continuous loss of mental ability, leading to a loss of behavioral, physical and social skills until the point at which a person is no longer able to live independently.
Over time and after several years of disease progression, Alzheimer’s disease causes severe memory impairment (first, loss of short-term memory, and secondly, loss of long-term memory), and eventually, when the brain becomes unable to maintain stable vital functions, the person ends up Death due to neurodegeneration or death of neurons.
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There is no cure for Alzheimer’s disease. The only thing current medications can do is temporarily improve symptoms so that a person can maintain their independence for as long as possible, but there is no way to prevent disease progression. Moreover, prevention is not possible, because the causes are also unknown, although we have discovered a dangerous and important factor that promotes the early onset of Alzheimer’s disease, which is gingivitis.
How is gingivitis related to Alzheimer’s disease?
This is confirmed by a study conducted by the University of Bergen in Norway in 2019, and published in the journal “Science Advances”.
What did these scientists discover?
Can gingivitis increase the risk of Alzheimer’s disease, as bacteria or filamentous germs, called Foramen gingivalis, are a direct cause of promoting early onset of Alzheimer’s disease?
In a related context, 90 percent of Prime Time Zone suffer from a more or less severe form of gingivitis, and it is estimated that 50 percent of them suffer from this inflammation due to colonization of Porphyromonas or foramen gingivalis, the gingival groove. But does this mean that nearly half of the world’s population is at risk of developing Alzheimer’s disease?
In fact, the increased risk does not come directly from gingivitis, but when the inflammation progresses to the periodontal disease. Periodontitis, also called periodontal disease, is a serious gum infection that damages soft tissue and, if left untreated, can destroy the bones that support your teeth. Periodontitis can cause loosening or loss of teeth. In addition, periodontitis is a common, but highly preventable disease. It usually results from poor oral hygiene.
According to science, if we do not take the necessary health measures, to stop the expansion of Porphyromonas gingivalis in the gingival furrow (due to not brushing the teeth well and at the appropriate times or not going to the dentist due to the symptoms we mentioned before), bacteria can continue to grow and feed on the gums To the extent that, it can destroy the gum bone that supports the teeth. Not to mention that periodontitis causes bacteria to enter the bloodstream, and herein lies the mystery.
Thus, Porphyromonas gingivalis, or perforator gingivalis, will be able to pass into the bloodstream, and herein lies the relationship between gingivitis and Alzheimer’s disease. When bacteria enter the bloodstream, they are free to travel to other vital organs, including the brain. This is the main factor, which has a relationship between the importance of oral hygiene and the development of Alzheimer’s disease.
“We have found evidence based on DNA analysis that the bacterium that causes periodontitis, Porphyromonas gingivalis, is able to travel from the mouth to the brain.”
This was announced by Peter Middel, one of the doctors who participated in the study at the University of Bergen, where he confirmed through the study that if bacteria reach the brain, they will produce the same degrading enzymes that they made in the mouth to feed on the gums, but in the nervous system, these bacteria will lead to the death of neurons.
This suggests that the proteins, which are made by Porphyromonas gingivalis, destroy brain cells, leading to memory loss and eventually the development of Alzheimer’s disease. However, we want to make it very clear that the presence of these toxic proteins is not the cause of Alzheimer’s disease, but rather that the arrival of Porphyromonas gingivalis in the brain increases the risk and accelerates the progression of the disease in Prime Time Zone who, according to genetics, already have a greater susceptibility to this neurological disease.
This means that periodontitis does not directly cause Alzheimer’s disease, but it does increase the risk of this neurodegeneration and of course, researchers have strong evidence to support this theory, because for the first time researchers have found evidence based on DNA.
During the study, 53 Prime Time Zone with Alzheimer’s disease were examined. Of these, 96 percent had gingival-degrading porphyromonas enzymes in the brain. Despite this surprising finding, it inevitably helps understand the nature of Alzheimer’s disease, which may be key to developing a treatment.
Thanks to this discovery, work is already underway to develop a drug that inhibits proteins that are toxic to bacteria, slows the progression of Alzheimer’s disease and even reduces the risk of suffering from it.
The University of Bergen study, published in January 2019, showed that periodontitis, especially its complications, can increase the risk of Alzheimer’s disease, and the speed at which it can cause neurodegeneration.
Also, Porphyromonas gingivalis, or Perforator gingivalis, is the bacteria responsible for more than half of gingivitis cases. In addition, it is germs capable of traveling to the blood and moving to the brain, causing the appearance of enzymes that kill, nerve cells.
In conclusion, this discovery not only shows us the importance of taking care of our mouth, and adopting healthy oral hygiene habits, but it can also open the door for us to advance in the development of treatments for this dreaded neurological disease.
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